Lung Transplantation & Advanced Therapies

Breakthroughs in lung transplantation & advanced therapies are improving survival rates and expanding eligibility criteria for patients with end-stage lung disease. Innovations in ex vivo lung perfusion, donor lung bioengineering, and tolerance-inducing immunomodulation are helping address the persistent challenge of organ shortages and rejection. Multidisciplinary care models now coordinate pre-transplant optimization and post-transplant surveillance using non-invasive biomarkers and imaging. Lung Transplantation & Advanced Therapies also includes regenerative strategies like stem cell therapy, decellularized scaffolds, and gene editing technologies, offering hope for patients previously considered ineligible for transplantation. The ethical, economic, and logistical implications of these therapies are actively under debate, demanding robust policy and clinical frameworks. Global registries, transplant networks, and cross-border collaborations are essential to improve access and outcomes as science reshapes what is surgically and biologically possible.