Bronchopulmonary dysplasia (BPD) is a persistent lung condition primarily affecting preterm infants who require prolonged respiratory support, including mechanical ventilation or supplemental oxygen. The disorder arises from disrupted alveolar and vascular growth, often compounded by inflammatory processes, oxidative stress, and injury related to ventilatory devices. Infants with BPD may experience labored breathing, low oxygen saturation, frequent respiratory infections, feeding difficulties, and delayed growth. Early recognition of high-risk infants—considering factors such as gestational age, birth weight, duration of mechanical ventilation, and comorbidities—is crucial to prevent progression and reduce long-term complications. Timely diagnosis allows clinicians to tailor interventions that support both immediate respiratory function and future lung development.
Management of BPD involves a comprehensive, multidisciplinary strategy that integrates respiratory, nutritional, and developmental care. Respiratory support focuses on minimizing lung injury while optimizing oxygenation, often using non-invasive ventilation, low-pressure mechanical ventilation, or carefully titrated oxygen therapy. Pharmacologic therapies, including diuretics, inhaled bronchodilators, and cautious corticosteroid use, help alleviate inflammation and improve lung compliance. Nutritional optimization, vigilant infection prevention, and regular assessment of growth and neurodevelopment are essential to long-term outcomes. Family engagement and caregiver education support adherence to home care plans and reduce rehospitalization risks. Advances in neonatal intensive care, individualized ventilation strategies, and post-discharge follow-up programs have markedly improved survival rates and functional outcomes. Modern bronchopulmonary dysplasia care emphasizes proactive, holistic interventions aimed at promoting lung maturation, preventing chronic complications, and supporting overall development in this vulnerable population.
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