A cough that persists beyond eight weeks can be both disruptive and indicative of underlying pathology, requiring thorough clinical evaluation. Chronic cough may stem from respiratory conditions such as asthma, COPD, or interstitial lung disease, but non-respiratory factors like gastroesophageal reflux or post-nasal drip are also frequent contributors. Accurate assessment involves detailed patient history, physical examination, and diagnostic testing that may include spirometry, imaging, and pH monitoring. Identifying the root cause is essential to avoid mismanagement and unnecessary treatments.
The process of chronic cough diagnosis is increasingly structured, relying on systematic exclusion and stepwise testing to narrow down possible causes. Clinicians often employ therapeutic trials, such as inhaled corticosteroids or proton pump inhibitors, to confirm suspected etiologies. New diagnostic tools, including cough frequency monitoring and biomarker analysis, are enhancing the objectivity of assessment. Multidisciplinary input from pulmonologists, gastroenterologists, and ENT specialists often ensures a more accurate diagnosis. Once the underlying cause is identified, management can be individualized, improving symptom control and quality of life. With growing research into neural hypersensitivity and emerging antitussive agents, the field continues to evolve toward more effective and targeted care for patients with persistent cough.
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